Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury

BACKGROUND: Toll like receptors (TLRs) signaling pathways, including the adaptor protein Mal encoded by the TIRAP gene, play a central role in the development of acute lung injury (ALI). Recently, the TIRAP variants have been described association with susceptibility to inflammatory diseases. The ai...

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Bibliographic Details
Main Authors: Song, Zhenju, Tong, Chaoyang, Sun, Zhan, Shen, Yao, Yao, Chenling, Jiang, Jinjun, Yin, Jun, Gao, Lei, Song, Yuanlin, Bai, Chunxue
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001691/
https://ncbi.nlm.nih.gov/pubmed/21118491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-168
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