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Purification, crystallization and preliminary X-ray analysis of a fusion of the LIM domains of LMO2 and the LID domain of Ldb1

LMO2 (LIM domain only 2), also known as rhombotin-2, is a transcriptional regulator that is essential for normal haematopoietic development. In malignant haematopoiesis, its ectopic expression in T cells is involved in the pathogenesis of leukaemia. LMO2 contains four zinc-finger domains and binds t...

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Autori principali: El Omari, Kamel, Porcher, Catherine, Mancini, Erika J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001649/
https://ncbi.nlm.nih.gov/pubmed/21045296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309110032872
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