Vaccinia-Related Kinase 1 Is Required for the Maintenance of Undifferentiated Spermatogonia in Mouse Male Germ Cells

Vaccinia-related kinase 1 (VRK1) is a crucial protein kinase for mitotic regulation. VRK1 is known to play a role in germ cell development, and its deficiency results in sterility. Here we describe that VRK1 is essential for the maintenance of spermatogonial stem cells. To determine whether VRK1 pla...

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Main Authors: Choi, Yoon Ha, Park, Choon-Ho, Kim, Wanil, Ling, Hua, Kang, Aram, Chang, Matthew Wook, Im, Sun-Kyoung, Jeong, Hyun-Woo, Kong, Young-Yun, Kim, Kyong-Tai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001494/
https://ncbi.nlm.nih.gov/pubmed/21179456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015254
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