Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

Rationale: Pulmonary arterial hypertension (PAH) is a progressive condition with a poor prognosis. Platelet-derived growth factor receptor (PDGFR) signaling plays an important role in its pathobiology. Objectives: To assess safety, tolerability, and efficacy of the PDGFR inhibitor imatinib in patien...

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Detalhes bibliográficos
Main Authors: Ghofrani, Hossein A., Morrell, Nicholas W., Hoeper, Marius M., Olschewski, Horst, Peacock, Andrew J., Barst, Robyn J., Shapiro, Shelley, Golpon, Heiko, Toshner, Mark, Grimminger, Friedrich, Pascoe, Steve
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
E. Pulmonary Vascular Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001259/
https://ncbi.nlm.nih.gov/pubmed/20581169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0123OC
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