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Down-regulation of Myc Is Essential for Terminal Erythroid Maturation

Terminal differentiation of mammalian erythroid progenitors involves 4–5 cell divisions and induction of many erythroid important genes followed by chromatin and nuclear condensation and enucleation. The protein levels of c-Myc (Myc) are reduced dramatically during late stage erythroid maturation, c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jayapal, Senthil Raja, Lee, Kian Leong, Ji, Peng, Kaldis, Philipp, Lim, Bing, Lodish, Harvey F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001006/
https://ncbi.nlm.nih.gov/pubmed/20940306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181073
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