Gradient of Increasing Aurora B Kinase Activity Is Required for Cells to Execute Mitosis

INCENP, Borealin, Survivin, and Aurora B kinase comprise the chromosomal passenger complex, an essential regulator of mitotic events. INCENP (inner centromere protein) binds and activates Aurora B through a feedback loop involving phosphorylation of a Thr-Ser-Ser (TSS) motif near the INCENP C termin...

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Main Authors: Xu, Zhenjie, Vagnarelli, Paola, Ogawa, Hiromi, Samejima, Kumiko, Earnshaw, William C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000998/
https://ncbi.nlm.nih.gov/pubmed/20956539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.181545
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