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Chemical Reactivities of Cysteine Substitutions in Subunit a of ATP Synthase Define Residues Gating H(+) Transport from Each Side of the Membrane

Subunit a plays a key role in coupling H(+) transport to rotations of the subunit c-ring in F(1)F(o) ATP synthase. In Escherichia coli, H(+) binding and release occur at Asp-61 in the middle of the second transmembrane helix (TMH) of F(o) subunit c. Based upon the Ag(+) sensitivity of Cys substitute...

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Detalhes bibliográficos
Main Authors: Dong, Hui, Fillingame, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000962/
https://ncbi.nlm.nih.gov/pubmed/20943664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175844
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