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Proline Periodicity Modulates the Self-assembly Properties of Elastin-like Polypeptides

Elastin is a self-assembling protein of the extracellular matrix that provides tissues with elastic extensibility and recoil. The monomeric precursor, tropoelastin, is highly hydrophobic yet remains substantially disordered and flexible in solution, due in large part to a high combined threshold of...

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Bibliographic Details
Main Authors: Muiznieks, Lisa D., Keeley, Fred W.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000959/
https://ncbi.nlm.nih.gov/pubmed/20947499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164467
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