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Modeled microgravity and hindlimb unloading sensitize osteoclast precursors to RANKL mediated osteoclastogenesis

Mechanical forces are essential to maintain skeletal integrity, and microgravity exposure leads to bone loss. The underlying molecular mechanisms leading to the changes in osteoblasts and osteoclast differentiation and function remain be to fully elucidated. Due to the infrequency of spaceflights an...

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Detaylı Bibliyografya
Asıl Yazarlar: Saxena, Ritu, Pan, George, Dohm, Erik D., McDonald, Jay M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000895/
https://ncbi.nlm.nih.gov/pubmed/20589403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00774-010-0201-4
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