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Contribution of VANGL2 mutations to isolated neural tube defects
Vangl2 was identified as the gene defective in the Looptail mouse model for neural tube defects (NTDs). This gene forms part of the planar cell polarity pathway, also called the non-canonical Frizzled/Dishevelled pathway, which mediates the morphogenetic process of convergent extension essential for...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3000889/ https://ncbi.nlm.nih.gov/pubmed/20738329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1399-0004.2010.01515.x |
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