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Characterization and Comparison of Two Binding Sites on Obscurin for Small Ankyrin 1(†)

Obscurin A, a ~720kDa modular protein of striated muscles, binds to small ankyrin 1 (sAnk1, Ank 1.5), an integral protein of the sarcoplasmic reticulum, through two distinct carboxy-terminal sequences, Obsc(6316–6436) and Obsc(6236–6260). We hypothesized that these sequences differ in affinity, but...

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Detalhes bibliográficos
Main Authors: Busby, Ben, Willis, Chris D., Ackermann, Maegen A., Kontrogianni-Konstantopoulos, Aikaterini, Bloch, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000613/
https://ncbi.nlm.nih.gov/pubmed/20949908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101165p
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