Connexin hemichannel-mediated CO(2)-dependent release of ATP in the medulla oblongata contributes to central respiratory chemosensitivity

Arterial [Image: see text], a major determinant of breathing, is detected by chemosensors located in the brainstem. These are important for maintaining physiological levels of [Image: see text] in the blood and brain, yet the mechanisms by which the brain senses CO(2) remain controversial. As ATP re...

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Detalhes bibliográficos
Main Authors: Huckstepp, Robert T R, id Bihi, Rachid, Eason, Robert, Spyer, K Michael, Dicke, Nikolai, Willecke, Klaus, Marina, Nephtali, Gourine, Alexander V, Dale, Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000581/
https://ncbi.nlm.nih.gov/pubmed/20736421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.192088
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