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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

In the nucleus of eukaryotic cells, nascent transcripts are associated with heterogeneous nuclear ribonucleoprotein (hnRNP) particles that are nucleated by hnRNP C. Despite their abundance however, it remained unclear whether these particles control pre-mRNA processing. Here, we developed individual...

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Bibliografske podrobnosti
Main Authors: König, Julian, Zarnack, Kathi, Rot, Gregor, Curk, Tomaž, Kayikci, Melis, Zupan, Blaž, Turner, Daniel J., Luscombe, Nicholas M., Ule, Jernej
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000544/
https://ncbi.nlm.nih.gov/pubmed/20601959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1838
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