A Highly Sensitive Ultra Performance Liquid Chromatography-Tandem Mass Spectrometric (UPLC-MS/MS) Technique for Quantitation of Protein Free and Bound Efavirenz (EFV) in Human Seminal and Blood Plasma

A combined UPLC-tandem mass spectrometric (UPLC-MS/MS) technique has been validated for quantitation of protein free efavirenz (EFV) as well as total concentrations of EFV in human blood and seminal plasma. The analytical method possesses capabilities for concentration measurements of EFV ranging fr...

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Autores principales: Avery, Lindsay B., Parsons, Teresa L., Meyers, David J., Hubbard, Walter C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000541/
https://ncbi.nlm.nih.gov/pubmed/21036679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.011
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