Analysis of Ca(v)1.2 and Ryanodine Receptor Clusters in Rat Ventricular Myocytes

We analyzed the distribution of ryanodine receptor (RyR) and Ca(v)1.2 clusters in adult rat ventricular myocytes using three-dimensional object-based colocalization metrics. We found that ∼75% of the Ca(v)1.2 clusters and 65% of the RyR clusters were within couplons, and both were roughly two and a...

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Bibliographic Details
Main Authors: Scriven, David R.L., Asghari, Parisa, Schulson, Meredith N., Moore, Edwin D.W.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Muscle, Motility, and Motor Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000512/
https://ncbi.nlm.nih.gov/pubmed/21156134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.008
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