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Universality in the Timescales of Internal Loop Formation in Unfolded Proteins and Single-Stranded Oligonucleotides

Understanding the rate at which various parts of a molecular chain come together to facilitate the folding of a biopolymer (e.g., a protein or RNA) into its functional form remains an elusive goal. Here we use experiments, simulations, and theory to study the kinetics of internal loop closure in dis...

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Detalhes bibliográficos
Main Authors: Cheng, Ryan R., Uzawa, Takanori, Plaxco, Kevin W., Makarov, Dmitrii E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000509/
https://ncbi.nlm.nih.gov/pubmed/21156138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.017
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