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Mammalian Target of Rapamycin Signaling in the Spinal Cord Is Required for Neuronal Plasticity and Behavioral Hypersensitivity Associated With Neuropathy in the Rat

The protein kinase mammalian target of rapamycin (mTOR) regulates mRNA translation and is inhibited by rapamycin. Signaling pathways involving mTOR are implicated in physiological and pathophysiological processes. We determined the spinal effects of the rapamycin analogue cell cycle inhibitor (CCI)-...

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Detalhes bibliográficos
Main Authors: Asante, Curtis O., Wallace, Victoria C., Dickenson, Anthony H.
Formato: Artigo
Idioma:Inglês
Publicado em: Churchill Livingstone 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000494/
https://ncbi.nlm.nih.gov/pubmed/20452291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2010.03.013
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