Amino acid derivatives are substrates or non-transported inhibitors of the amino acid transporter PAT2 (slc36a2)

The H(+)-coupled amino acid transporter PAT2 (SLC36A2) transports the amino acids proline, glycine, alanine and hydroxyproline. A physiological role played by PAT2 in amino acid reabsorption in the renal proximal tubule is demonstrated by mutations in SLC36A2 that lead to an iminoglycinuric phenotyp...

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Détails bibliographiques
Auteurs principaux: Edwards, Noel, Anderson, Catriona M.H., Gatfield, Kelly M., Jevons, Mark P., Ganapathy, Vadivel, Thwaites, David T.
Format: Artigo
Langue:Inglês
Publié: Elsevier Pub. Co 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000476/
https://ncbi.nlm.nih.gov/pubmed/20691150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.07.032
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