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Design and Optimization of Coin-Shaped Microreactor Chips for PET Radiopharmaceutical Synthesis

An integrated elastomeric microfluidic device, with a footprint the size of a postage stamp, has been designed and optimized for multistep radiosynthesis of PET tracers. METHODS: The unique architecture of the device is centered around a 5-μL coin-shaped reactor, which yields reaction efficiency and...

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Detalhes bibliográficos
Main Authors: Elizarov, Arkadij M., van Dam, R. Michael, Shin, Young Shik, Kolb, Hartmuth C., Padgett, Henry C., Stout, David, Shu, Jenny, Huang, Jiang, Daridon, Antoine, Heath, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000316/
https://ncbi.nlm.nih.gov/pubmed/20124050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.065946
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