Concomitant deletions of tumor suppressor genes MEN1 and AIP are essential for the pathogenesis of the brown fat tumor hibernoma

Hibernomas are benign tumors with morphological features resembling brown fat. They consistently display cytogenetic rearrangements, typically translocations, involving chromosome band 11q13. Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor...

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Detalhes bibliográficos
Main Authors: Nord, Karolin H., Magnusson, Linda, Isaksson, Margareth, Nilsson, Jenny, Lilljebjörn, Henrik, Domanski, Henryk A., Kindblom, Lars-Gunnar, Mandahl, Nils, Mertens, Fredrik
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000312/
https://ncbi.nlm.nih.gov/pubmed/21078971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013512107
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