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CYCLOSPORINE METABOLISM AND PHARMACOKINETICS FOLLOWING INTRAVENOUS AND ORAL ADMINISTRATION IN THE DOG

The influence of assay method on single dose cyclosporine (CsA) pharmacokinetics was studied in nine dogs receiving either i.v. or oral CsA. Samples were drawn from hepatic, portal, and systemic veins at various times after the dose and CsA levels were determined by radioimmunoassay (RIA) and high-p...

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Autors principals: Gridelli, Bruno, Scanlon, Lenia, Pellicci, Riccardo, LaPointe, Real, DeWolf, Andre, Seltman, Howard, Diven, Warren, Shaw, Byers, Starzl, Thomas, Sanghvi, Ajit
Format: Artigo
Idioma:Inglês
Publicat: 1986
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000222/
https://ncbi.nlm.nih.gov/pubmed/3952805
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