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Paradoxical Acceleration of Dithiothreitol-Induced Aggregation of Insulin in the Presence of a Chaperone

The kinetics of dithiothreitol (DTT)-induced aggregation of human recombinant insulin and the effect of α-crystallin, a representative of the family of small heat shock proteins, on the aggregation process have been studied using dynamic light scattering technique. Analysis of the distribution of th...

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Bibliografiske detaljer
Main Authors: Bumagina, Zoya, Gurvits, Bella, Artemova, Natalya, Muranov, Konstantin, Kurganov, Boris
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000100/
https://ncbi.nlm.nih.gov/pubmed/21151456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11114556
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