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Targeted deletion of endothelial lipase increases HDL particles with anti-inflammatory properties both in vitro and in vivo

Previous studies have shown that targeted deletion of endothelial lipase (EL) markedly increases the plasma high density lipoprotein cholesterol (HDL-C) level in mice. However, little is known about the functional quality of HDL particles after EL inhibition. Therefore, the present study assessed th...

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Detalhes bibliográficos
Main Authors: Hara, Tetsuya, Ishida, Tatsuro, Kojima, Yoko, Tanaka, Hanayo, Yasuda, Tomoyuki, Shinohara, Masakazu, Toh, Ryuji, Hirata, Ken-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999926/
https://ncbi.nlm.nih.gov/pubmed/20926433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M008417
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