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Structural Analysis of HIV-1 Maturation Using Cryo-Electron Tomography
HIV-1 buds form infected cells in an immature, non-infectious form. Maturation into an infectious virion requires proteolytic cleavage of the Gag polyprotein at five positions, leading to a dramatic change in virus morphology. Immature virions contain an incomplete spherical shell where Gag is arran...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999899/ https://ncbi.nlm.nih.gov/pubmed/21151640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001215 |
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