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Is Huntington disease a developmental disorder?
The recently discovered roles of huntingtin in non-differentiated cells indicate that it is a key molecule in brain development. Humbert argues that the haploinsufficiency of wild-type huntingtin in Huntington disease might lead to various cellular alterations well before the onset of symptoms and u...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999873/ https://ncbi.nlm.nih.gov/pubmed/21102640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.182 |
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