Uncovering new substrates for Aurora A kinase

Aurora A is a serine/threonine kinase that is essential for a wide variety of cell-cycle-related events, but only a small number of its substrates are known. We present and validate a strategy by which to identify Aurora A substrates and their phosphorylation sites. We developed a computational appr...

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Autori principali: Sardon, Teresa, Pache, Roland A, Stein, Amelie, Molina, Henrik, Vernos, Isabelle, Aloy, Patrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999863/
https://ncbi.nlm.nih.gov/pubmed/21072059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.171
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