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A Conserved Helical Capping Hydrogen Bond in PAS Domains Controls Signaling Kinetics in the Superfamily Prototype Photoactive Yellow Protein

PAS domains form a divergent protein superfamily with more than 20,000 members that perform a wide array of sensing and regulatory functions in all three domains of life. Only 9 residues are well-conserved in PAS domains, with an Asn residue at the start of α-helix 3 showing the strongest conservati...

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Detalhes bibliográficos
Main Authors: Kumauchi, Masato, Kaledhonkar, Sandip, Philip, Andrew F., Wycoff, James, Hara, Miwa, Li, Yunxing, Xie, Aihua, Hoff, Wouter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999845/
https://ncbi.nlm.nih.gov/pubmed/20954744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja107716r
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