Suppression of gastric acid increases the risk of developing Immunoglobulin E-mediated drug hypersensitivity: human diclofenac sensitization and a murine sensitization model

BACKGROUND: Hypersensitivity reactions towards non-steroidal anti-inflammatory drugs (NSAID) are common, although true allergies are detectable only in a subgroup of patients. The current study was prompted by a case observation, where a patient experienced generalized urticaria following his second...

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Main Authors: Riemer, A. B., Gruber, S., Pali-Schöll, I., Kinaciyan, T., Untersmayr, E., Jensen-Jarolim, E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999742/
https://ncbi.nlm.nih.gov/pubmed/19817752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2009.03363.x
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