ロード中...

Serendipitous Discovery of α-Hydroxyalkyl Esters as β-Lactamase Substrates

O-(1-Carboxy-1-alkyloxycarbonyl) hydroxamates were found to spontaneously decarboxylate in aqueous neutral buffer to form O-(2-hydroxyalkylcarbonyl) hydroxamates. While the former molecules do not react rapidly with serine β-lactamases, the latter are quite good substrates of representative classes...

詳細記述

保存先:
書誌詳細
主要な著者: Pelto, Ryan B., Pratt, R. F.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999657/
https://ncbi.nlm.nih.gov/pubmed/21087009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101071r
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!