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Development of Central Nervous System Metastases in Patients with Advanced Non-Small Cell Lung Cancer and Somatic EGFR Mutations Treated with Gefitinib or Erlotinib

PURPOSE: Gefitinib and erlotinib can penetrate into the central nervous system (CNS) and elicit responses in patients with brain metastases (BM) from non-small cell lung cancer (NSCLC). However, there is incomplete data about their impact on the development and control of CNS metastases. EXPERIMENTA...

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Autors principals: Heon, Stephanie, Yeap, Beow Y., Britt, Gregory J., Costa, Daniel B., Rabin, Michael S., Jackman, David M., Johnson, Bruce E.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999638/
https://ncbi.nlm.nih.gov/pubmed/21030498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-1588
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