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Nanoparticle Design Optimization for Enhanced Targeting: Monte Carlo Simulations

Using computer simulations, we systematically studied the influence of different design parameters of a spherical nanoparticle tethered with monovalent ligands on its targeting efficiency of planar cell surfaces containing mobile receptors. We investigate how the nanoparticle affinity can be affecte...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Shihu, Dormidontova, Elena E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999362/
https://ncbi.nlm.nih.gov/pubmed/20536119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm100248e
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