A Bayesian approach for identifying miRNA targets by combining sequence prediction and gene expression profiling

BACKGROUND: MicroRNAs (miRNAs) are single-stranded non-coding RNAs shown to plays important regulatory roles in a wide range of biological processes and diseases. The functions and regulatory mechanisms of most of miRNAs are still poorly understood in part because of the difficulty in identifying th...

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Main Authors: Liu, Hui, Yue, Dong, Zhang, Lin, Chen, Yidong, Gao, Shou-Jiang, Huang, Yufei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999342/
https://ncbi.nlm.nih.gov/pubmed/21143779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S3-S12
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