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Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors

We identify a secreted chemokine inhibitor encoded by orf virus (ORFV), the prototypic poxvirus of the Parapoxvirus genus, and show that it is related to the poxvirus type II CC-chemokine-binding proteins (CBP-II) produced by members of the Orthopoxvirus and Leporipoxvirus genera. The ORFV chemokine...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Seet, Bruce T., McCaughan, Catherine A., Handel, Tracy M., Mercer, Andrew, Brunetti, Craig, McFadden, Grant, Fleming, Stephen B.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14657392/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2336648100
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