Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

Recently, agonist antibodies to glucocorticoid-induced tumor necrosis factor receptor (GITR) (tumor necrosis factor receptor superfamily 18) have been shown to neutralize the suppressive activity of CD4(+)CD25(+) regulatory T cells. It was anticipated that this would be the role of the physiological...

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Bibliographic Details
Main Authors: Tone, Masahide, Tone, Yukiko, Adams, Elizabeth, Yates, Stephen F., Frewin, Mark R., Cobbold, Stephen P., Waldmann, Herman
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC299905/
https://ncbi.nlm.nih.gov/pubmed/14608036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2334901100
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