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Hepatospheres: Three dimensional cell cultures resemble physiological conditions of the liver

Studying physiological and pathophysiological mechanisms in the liver on a molecular basis is a challenging task. During two dimensional (2D) culture conditions hepatocytes dedifferentiate rapidly by losing metabolic functions and structural integrity. Hence, inappropriate 2D hepatocellular models h...

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Detaylı Bibliyografya
Asıl Yazarlar: van Zijl, Franziska, Mikulits, Wolfgang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Baishideng Publishing Group Co., Limited 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998947/
https://ncbi.nlm.nih.gov/pubmed/21160950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v2.i1.1
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