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Facile Route to Tetrasubstituted Pyrazoles Utilizing Ceric Ammonium Nitrate

A convenient approach for the synthesis of tetrasubstituted pyrazoles is described. The method involves the treatment of 1,3-diketones and allyltrimethylsilane with CAN followed by cerium-catalyzed addition of substituted hydrazines to construct pyrazoles in good yields.

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Hlavní autoři: Devery, James J., Mohanta, Pramod K., Casey, Brian M., Flowers, Robert A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998890/
https://ncbi.nlm.nih.gov/pubmed/21151843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0029-1217163
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