Curcumin prevents leptin raising glucose levels in hepatic stellate cells by blocking translocation of glucose transporter-4 and increasing glucokinase

BACKGROUND AND PURPOSE: Hyperleptinemia is commonly found in obese patients, associated with non-alcoholic steatohepatitis and hepatic fibrosis. Hepatic stellate cells (HSCs) are the most relevant effectors during hepatic fibrogenesis. We recently reported that leptin stimulated HSC activation, whic...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Tang, Youcai, Chen, Anping
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2010
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998693/
https://ncbi.nlm.nih.gov/pubmed/20977462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00956.x
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