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Changes in Single K(+) Channel Behavior Induced by a Lipid Phase Transition

We show that the activity of an ion channel is correlated with the phase state of the lipid bilayer hosting the channel. By measuring unitary conductance, dwell times, and open probability of the K(+) channel KcsA as a function of temperature in lipid bilayers composed of POPE and POPG in different...

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Main Authors: Seeger, Heiko M., Aldrovandi, Laura, Alessandrini, Andrea, Facci, Paolo
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998624/
https://ncbi.nlm.nih.gov/pubmed/21112292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.10.042
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