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Improved Hidden Markov Models for Molecular Motors, Part 1: Basic Theory

Hidden Markov models (HMMs) provide an excellent analysis of recordings with very poor signal/noise ratio made from systems such as ion channels which switch among a few states. This method has also recently been used for modeling the kinetic rate constants of molecular motors, where the observable...

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Autors principals: Müllner, Fiona E., Syed, Sheyum, Selvin, Paul R., Sigworth, Fred J.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998602/
https://ncbi.nlm.nih.gov/pubmed/21112293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.067
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