Effects of chronic fentanyl administration on physical performance of aged rats

There is growing concern over the increasing use of opioids to treat chronic pain in the elderly primarily because of the potential increased sensitivity to the adverse side effects. Here, we use a preclinical model (male Brown Norway X F344 rats aged 12, 18, 24, and 30 months) to describe the outco...

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Main Authors: Mitzelfelt, Jeremiah D., DuPree, Jameson P., Seo, Dong-oh, Carter, Christy S., Morgan, Drake
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998590/
https://ncbi.nlm.nih.gov/pubmed/20951790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2010.10.004
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