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Reactive nitrogen and oxygen species, and iron sequestration contribute to macrophage-mediated control of Encephalitozoon cuniculi (Phylum Microsporidia) infection in vitro and in vivo

Encephalitozoon cuniculi (Phylum Microsporidia) infects a wide range of mammals, and replicates within resting macrophages. Activated macrophages, conversely, inhibit replication and destroy intracellular organisms. These studies were performed to assess mechanisms of innate immune responses express...

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Bibliographic Details
Main Authors: Didier, Elizabeth S., Bowers, Lisa C., Martin, Aaron D., Kuroda, Marcelo J., Khan, Imtiaz A., Didier, Peter J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998546/
https://ncbi.nlm.nih.gov/pubmed/20888426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2010.09.010
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