IL-6-Dependent PGE2 Secretion by Mesenchymal Stem Cells Inhibits Local Inflammation in Experimental Arthritis

BACKGROUND: Based on their capacity to suppress immune responses, multipotent mesenchymal stromal cells (MSC) are intensively studied for various clinical applications. Although it has been shown in vitro that the immunomodulatory effect of MSCs mainly occurs through the secretion of soluble mediato...

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Bibliographic Details
Main Authors: Bouffi, Carine, Bony, Claire, Courties, Gabriel, Jorgensen, Christian, Noël, Danièle
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998425/
https://ncbi.nlm.nih.gov/pubmed/21151872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014247
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