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Constitutive Activation of PrfA Tilts the Balance of Listeria monocytogenes Fitness Towards Life within the Host versus Environmental Survival

PrfA is a key regulator of Listeria monocytogenes pathogenesis and induces the expression of multiple virulence factors within the infected host. PrfA is post-translationally regulated such that the protein becomes activated upon bacterial entry into the cell cytosol. The signal that triggers PrfA a...

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Detalhes bibliográficos
Main Authors: Bruno, Joseph C., Freitag, Nancy E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998416/
https://ncbi.nlm.nih.gov/pubmed/21151923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015138
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