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The Effects of Demography and Linkage on the Estimation of Selection and Mutation Parameters

We explore the effects of demography and linkage on a maximum-likelihood (ML) method for estimating selection and mutation parameters in a reversible mutation model. This method assumes free recombination between sites and a randomly mating population of constant size and uses information from both...

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Main Authors: Zeng, Kai, Charlesworth, Brian
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998320/
https://ncbi.nlm.nih.gov/pubmed/20923980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.122150
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