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Glucose Stimulation of Hypothalamic MCH Neurons Involves K(ATP) Channels, is Modulated by UCP2, and Regulates Peripheral Glucose Homeostasis

Blood glucose levels are tightly controlled, a process thought to be orchestrated primarily by peripheral mechanisms (insulin secretion by β-cells, and insulin action on muscle, fat and liver). The brain also plays an important, albeit less well-defined role. Subsets of neurons in the brain are exci...

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Detalhes bibliográficos
Main Authors: Kong, Dong, Vong, Linh, Parton, Laura E., Ye, Chianping, Tong, Qingchun, Hu, Xiaoxia, Choi, Brian, Brüning, Jens C., Lowell, Bradford B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998191/
https://ncbi.nlm.nih.gov/pubmed/21035764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.09.013
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