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Biomarker variance component estimation for exposure surrogate selection and toxicokinetic inference

Biomarkers are useful exposure surrogates given their ability to integrate exposures through all routes and to reflect interindividual differences in toxicokinetic processes. Also, biomarker concentrations tend to vary less than corresponding environmental measurements, making them less-biasing surr...

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Detalhes bibliográficos
Main Authors: Sobus, Jon R., Pleil, Joachim D., McClean, Michael D., Herrick, Robert F., Rappaport, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998189/
https://ncbi.nlm.nih.gov/pubmed/20851754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2010.09.006
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