Mutations in the Carboxyl-terminal SEC24 Binding Motif of the Serotonin Transporter Impair Folding of the Transporter

The serotonin transporter (SERT) is a member of the SLC6 family of solute carriers. SERT plays a crucial role in synaptic neurotransmission by retrieving released serotonin. The intracellular carboxyl terminus of various neurotransmitter transporters has been shown to be important for the correct de...

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Autores principales: El-Kasaby, Ali, Just, Herwig, Malle, Elisabeth, Stolt-Bergner, Peggy C., Sitte, Harald H., Freissmuth, Michael, Kudlacek, Oliver
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Protein Structure and Folding
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998113/
https://ncbi.nlm.nih.gov/pubmed/20889976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.118000
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