Butyrate-rich Colonic Microenvironment Is a Relevant Selection Factor for Metabolically Adapted Tumor Cells

The short chain fatty acid (SCFA) buyrate is a product of colonic fermentation of dietary fibers. It is the main source of energy for normal colonocytes, but cannot be metabolized by most tumor cells. Butyrate also functions as a histone deacetylase (HDAC) inhibitor to control cell proliferation and...

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Detalhes bibliográficos
Main Authors: Serpa, Jacinta, Caiado, Francisco, Carvalho, Tânia, Torre, Cheila, Gonçalves, Luís G., Casalou, Cristina, Lamosa, Pedro, Rodrigues, Margarida, Zhu, Zhenping, Lam, Eric W. F., Dias, Sérgio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998102/
https://ncbi.nlm.nih.gov/pubmed/20926374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.156026
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