Alternatively Expressed Domains of AU-rich Element RNA-binding Protein 1 (AUF1) Regulate RNA-binding Affinity, RNA-induced Protein Oligomerization, and the Local Conformation of Bound RNA Ligands

AU-rich element RNA-binding protein 1 (AUF1) binding to AU-rich elements (AREs) in the 3′-untranslated regions of mRNAs encoding many cytokines and other regulatory proteins modulates mRNA stability, thereby influencing protein expression. AUF1-mRNA association is a dynamic paradigm directed by vari...

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Detalhes bibliográficos
Main Authors: Zucconi, Beth E., Ballin, Jeff D., Brewer, Brandy Y., Ross, Christina R., Huang, Jun, Toth, Eric A., Wilson, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998080/
https://ncbi.nlm.nih.gov/pubmed/20926381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.180182
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