“Upregulation of STREX splice variant of the large conductance Ca(2+)-activated potassium (BK) channel in a rat model of mesial temporal lobe epilepsy”

Functional properties of large conductance Ca(2+) activated potassium (BK) channels are determined by complex alternative splicing of the Kcnma1 gene encoding the alpha pore-forming subunit. Inclusion of the STREX exon in a C-terminal splice site is dynamically regulated and confers enhanced Ca(2+)...

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Détails bibliographiques
Auteurs principaux: Ermolinsky, Boris S., Skinner, Frank, Garcia, Ileana, Arshasamanb, Massoud F., Pacheco Otalora, Luis F., Zarei, Masoud M., Garrido-Sanabria, Emilio R.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997846/
https://ncbi.nlm.nih.gov/pubmed/20933547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neures.2010.09.011
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